Blood cells such as red blood and white blood cells flow in our blood. In the blood of patients with cancer, extremely small amount of cancer cells can be mixed in with blood cells. Researchers around the world are focusing their attention on these cancer cells known as circulating tumor cells (CTCs) that are linked to cancer metastasis.
To help find CTCs in the blood from the morphological cell information, at Hamamatsu Photonics, we are researching and developing 3D imaging flow cytometers that are able to visualize the internal structure of individual cells.
Quantitatie Phase Microscope (QPM) is a microscope using interference of light, which observes the morphology of live cells without staining. QPM is able to measure nanometer-scale morphological features and it has a potential to quantify subtle changes in live cells before and after drug treatment or/and differentiation. We are developing image cytometry system with QPM in order to contribute to advanced biomedical researches such as regenerative medicine.
The breast cancer incidence rate has been increasing in Japanese women. A measurement technology for diagnosing and monitoring responses to the treatment is important to improve the QOL (Quality of Life) of breast cancer patients. The near infrared spectroscopy (NIRS) is a noninvasive measurement technique to quantify the absorption and scattering coefficients, hemoglobin concentration, and tissue oxygen saturation in the biological tissue. The light used for NIRS measurement is in the wavelength range 700 nm to 1100 nm that has relatively higher transmittance than other wavelengths. NIRS is expected to be useful for detecting change in those parameters due to growth or shrinkage of the breast cancer. The optical mammography, which is a NIRS system designed for breast measurement, will provide earlier detection and easier monitoring of the breast cancer.
Neutrophils, a type of leukocytes are mainly responsible for innate immunity. They defend our bodies against foreign invaders such as bacteria. We have developed a method to simultaneously monitor two events occurring within and around leukocytes during the innate immune response. As a result, the cell-based assay to measure antioxidant/anti-inflammatory/immunostimulant activities has been established as a method to assess the functionality of food components. We are now developing a novel system to measure the neutrophil activation even in a small amount (3 μl) of whole blood easily and accurately. This system can detect the neutrophil overactivation related to inflammation and evaluate the balance between oxidants and antioxidants in vivo, therefore it is expected to be used as the health (presymptomatic disease) check marker.
Based on our PET technology accumulated over the years, we have succeeded in developing a PET probe to measure mitochondrial function for the first time in the world. We not only promote research on biological functions using our unique PET probes but also perform drug evaluation studies as contract researches.
(We comply with research ethics and make consideration to animal welfare in performing animal experiments.)
It looks like you’re in the . If this is not your location, please select the correct region and country below.
You're headed to Hamamatsu Photonics website for U.K. (English). If you want to view an other country's site, the optimized information will be provided by selecting options below.
For modern websites to work according to visitor’s expectations, they need to collect certain basic information about visitors. To do this, a site will create small text files which are placed on visitor’s devices (computer or mobile) - these files are known as cookies when you access a website. Cookies are used in order to make websites function and work efficiently. Cookies are uniquely assigned to each visitor and can only be read by a web server in the domain that issued the cookie to the visitor. Cookies cannot be used to run programs or deliver viruses to a visitor’s device.
Cookies do various jobs which make the visitor’s experience of the internet much smoother and more interactive. For instance, cookies are used to remember the visitor’s preferences on sites they visit often, to remember language preference and to help navigate between pages more efficiently. Much, though not all, of the data collected is anonymous, though some of it is designed to detect browsing patterns and approximate geographical location to improve the visitor experience.
Certain type of cookies may require the data subject’s consent before storing them on the computer.
This website uses two types of cookies:
There are two ways to manage cookie preferences.
If you wish to restrict or block web browser cookies which are set on your device then you can do this through your browser settings; the Help function within your browser should tell you how. Alternatively, you may wish to visit www.aboutcookies.org, which contains comprehensive information on how to do this on a wide variety of desktop browsers.
Occasionally, we may use internet tags (also known as action tags, single-pixel GIFs, clear GIFs, invisible GIFs and 1-by-1 GIFs) at this site and may deploy these tags/cookies through a third-party advertising partner or a web analytical service partner which may be located and store the respective information (including your IP-address) in a foreign country. These tags/cookies are placed on both online advertisements that bring users to this site and on different pages of this site. We use this technology to measure the visitors' responses to our sites and the effectiveness of our advertising campaigns (including how many times a page is opened and which information is consulted) as well as to evaluate your use of this website. The third-party partner or the web analytical service partner may be able to collect data about visitors to our and other sites because of these internet tags/cookies, may compose reports regarding the website’s activity for us and may provide further services which are related to the use of the website and the internet. They may provide such information to other parties if there is a legal requirement that they do so, or if they hire the other parties to process information on their behalf.
If you would like more information about web tags and cookies associated with on-line advertising or to opt-out of third-party collection of this information, please visit the Network Advertising Initiative website http://www.networkadvertising.org.
We use third-party cookies (such as Google Analytics) to track visitors on our website, to get reports about how visitors use the website and to inform, optimize and serve ads based on someone's past visits to our website.
You may opt-out of Google Analytics cookies by the websites provided by Google:
We inform you that in such case you will not be able to wholly use all functions of our website.