DIUTHAME Ionization assisting substrate


Hamamatsu offers ionization-assisting substrates called DIUTHAME that support ionization in mass spectrometry in place of matrix that is currently used for MALDI (Matrix-Assisted Laser Desorption/Ionization) and also eliminate the cumbersome sample pretreatment process. A13331-10-1 is suitable for small size samples. The effective area of the channel is Φ10 mm. A13331-10-1B can be used for blotting measurement.


  • NO matrix background noise
  • High reproducibility with minimal variation no matter who does the measurement
  • NO sample pretreatment required
  • High spatial resolution in imaging mass spectrometry ensured by nanometer-order structure

How DIUTHAME differs from conventional MALDI

Background noise None Matrix noise appears
Ease of handling Easy Expertise is required
Reproducibility High Not so high
Spatial resolution High Not so high
Measurement of high molecules Possible depending on samples Possible

Dimensional outlines (Unit mm)

A13331-10-1(For MS imaging) / A13331-10-1B(For blotting)


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