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MoxiePlex Multi-spectral imaging system
C16919-01
The MoxiePlex® Multi-spectral imaging system captures high-resolution images of entire tissue samples stained with multiple fluorescent dyes. These images play a pivotal role in evaluating and visualizing biomarker localization and expression levels, empowering researchers to perform comprehensive analysis.
MoxiePlex is a registered trademark of Hamamatsu Photonics K.K. (China, EU, Japan, Switzerland, UK).
Acquire high-resolution images with up to 9 channels
The MoxiePlex is designed to speed up multiplex immunofluorescence research by providing up to 9 channels across the entire tissue section.
With a 16 bit output, it delivers high-resolution imaging essential for image analysis. Additionally, the system is equipped with a state-of-the-art camera featuring high quantum efficiency across a 400 nm to 900 nm wavelength range, allowing for a broader selection of fluorescent reagents and enhanced biomarker detection.
Spectral sensitivity
Imaging examples
Akoya Biosciences MOTiF PD-1/PD-L1 Panel 7plex kit
Akoya Biosciences MOTiF PD-1/PD-L1 Panel 5plex kit
SignalStar™ Multiplex IHC Kit
Overlay image of DAPI (blue) and individual targets (white)
Compatible with BF
The MoxiePlex enables seamless superimposition of brightfield and fluorescence images within the Moxie software. It captures high-resolution images of H&E-stained, immunohistochemically (IHC)-stained, and specially stained samples, providing a comprehensive view of tissue morphology for in-depth observation and analysis.
H&E
IHC
Automated sample recognition and exposure time calculation
The MoxiePlex uses proprietary fluorescence optics technology and algorithms to automate sample recognition, scan range setting, focus position setting, and exposure time calculation. Users can choose between fully automated operation to minimize manual effort or manual adjustments for greater flexibility and control.
Features of each flow
Automatically recognizes the entire tissue sample and automatically calculates exposure time to acquire fluorescent images
The MoxiePlex enhances immunofluorescence imaging by automatically detecting tissue samples that are challenging to identify in brightfield imaging. It intelligently sets scan profiles and optimizes exposure time for precise fluorescent image acquisition, ensuring a seamless workflow and high accuracy. (Patent pending)
Specifications
| Product name | MoxiePlex Multi-spectral imaging system | |
|---|---|---|
| Product number | C16919-01 | |
| Cassette loader | Up to 60 slides | |
| Compatible glass slide | 75.0 mm to 76.0 mm × 25.0 mm to 26.0 mm (Thickness: 0.9 mm to 1.2 mm) |
|
| Objective lens | 20× NA 0.8 |
|
| Scanning resolution | 20x mode | 0.46 μm/pixel |
| 40x mode | 0.23 μm/pixel | |
| Brightfield scan speed | 20x mode | Approx. 60 s（15 mm × 15 mm） |
| 40x mode | Approx. 70 s（15 mm × 15 mm） | |
| Fluorescence throughput *1 | 20x mode | Approx. 12 min.（15 mm × 15 mm, 5 channels） |
| 40x mode | Approx. 14 min.（15 mm × 15 mm, 5 channels） | |
| Fluorescence camera | In-house sCMOS camera | |
| Z-stack feature | Included | |
| Image format | OME-TIFF (16 bit, 8 bit), NDPI (8 bit) | |
| Power supply | AC 100 V to AC 240 V | |
| Power consumption | Approx. 180 VA | |
*1 Fluorescence throughput: The time from loading the glass slide, macro photography, prefocusing 5 points, scanning, image processing, to unloading the glass slide.
Dimensions
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