European Drug Discovery Workshop

European Drug Discovery Workshop

FDSS Users Meeting in Leuven, Belgium

Videos/Recordings
Posters
Testimonials
Past/Other Events

The meeting featured presentations from European Functional Drug Screening experts and researchers using the technique across varied applications within drug discovery, safety toxicology and disease modeling. It brought together the FDSS community to share, learn and discuss how the system is being applied to today's problems and pioneering tomorrow's capabilities. The meeting was open to all our FDSS Users, as well as anyone interested in the fluorescence and luminescence kinetic plate readers.

Special edition: For the first time, we included a session dedicated to the screening of 3D cell cultures and unveiled our next-generation functional drug screening system, the FDSS GX!

Presentations given during previous FDSS user meetings are shared on this page. This highly scientific content on the latest drug screening and development from experts in the field.

Videos/Recordings

Session 1

FRET biosensors as a novel tool for membrane target screening

Dr. Marina Martina, Principal Scientist in cell biology unit, Axxam SpA

IP3R: function & dysfunction in human diseases

Dr. Geert Bultynck, KU Leuven

Exploring the function of IP3 receptors in induced pluripotent stem cells

Julius Rönkkö, University of Helsinki

Human iPSC derived iCell Cardiomyocytes² reproduce vagomimetic side effects of S1PR agonists therapy for Multiple Sclerosis

Thierry Capiod, Institut Necker Enfants Malades

Session 2

Microbrains for neuronal safety evaluation

Gautier Roussignol, Sanofi R&D

Effects of Cell Composition and Disease Genotype on Calcium Dynamics in iPSC-derived 3D Neural Spheres

Ouissame Mnie-Filali, FUJIFILM Cellular Dynamics

Magnetic 3D cell culture: New tools to overcome the limitations of

3D cell culture

Cyril Domenjoz, Greiner Bio-One

Posters

Using the waveforms of GPCR signaling dynamics in high throughput drug discovery

Sam Hoare, Luciana Leo, Thom Hughes, Anne Marie Quinn, Montana Molecular; Bozeman, MT, USA

Using the waveforms of GPCR signaling dynamics in high throughput drug discovery

Using the waveforms of GPCR signaling dynamics in high throughput drug discovery [432 KB/PDF]

Alternative Approaches to Enhance the Functional Complexity of Human iPSC-derived Cardiomyocytes in 2D and 3D

Ouissame Filali, Katherine Czysz, Megan K. Livingston, Rebecca K. Fiene, Nathan Meyer, Sarah Himmerich, Cara Rieger, Ravi Vaidyanathan and Coby B. Carlson, FUJIFILM Cellular Dynnamics, Inc., Madison, WI USA

Alternative Approaches to Enhance the Functional Complexity of Human iPSC-derived Cardiomyocytes in 2D and 3D

Alternative Approaches to Enhance the Functional Complexity of Human iPSC-derived Cardiomyocytes in 2D and 3D [2.3 MB/PDF]

Preliminary Investigations into Cav1.2 Ion Channel Cell Line: Potential of Calcium Imaging and Electrical Stimulation

Ayla Aksoy-Aksel, Timm Danker, Udo Kraushaar, NMI Natural and Medical Sciences Institute at the University Tübingen, Reutlingen, Germany

Preliminary Investigations into Cav1.2 Ion Channel Cell Line: Potential of Calcium Imaging and Electrical Stimulation

Preliminary Investigations into Cav1.2 Ion Channel Cell Line: Potential of Calcium Imaging and Electrical Stimulation [734 KB/PDF]

Characterization of Human iPSC-derived Induced Excitatory Neurons for Disease Modeling and Drug Discovery

Ouissame Filali, Robert Bradley, Junyi Ma, Ali Fathi, Rebecca Fiene, Clifford Hogan, Coby Carlson, Simon Hilcove, Scott Schachtele and Jing Liu, FUJIFILM Celullar Dynamics, Inc., Madison, WI USA

Characterization of Human iPSC-derived Induced Excitatory Neurons for Disease Modeling and Drug Discovery

Characterization of Human iPSC-derived Induced Excitatory Neurons for Disease Modeling and Drug Discovery [1.9 MB/PDF]

NAM-Related Robustness Analysis of Commercial hiPSC-Cardiomyocytes in the Light of Preclinical Cardiac Risk Assessment

B. Lickiss¹, M, Gossmann¹, P. Linder¹, E. Dragicevic², U. Thomas², R. Vaidyanathan³, O. Filali³, S. Stoelzle-Feix², M. George², N. Fertig²

¹innoVitro GmbH, Juelich, Germany, ²Nanion Technologies GmbH, Munich, Germany, ³Fujifilm Cellular Dynamics Inc. Madison, Wisconsin, USA

NAM-Related Robustness Analysis of Commercial hiPSC-Cardiomyocytes in the Light of Preclinical Cardiac Risk Assessment

NAM-Related Robustness Analysis of Commercial hiPSC-Cardiomyocytes in the Light of Preclinical Cardiac Risk Assessment [975 KB/PDF]

ELECTRICAL STIMULATION OF THE MYOSCREEN™ PLATFORM WITH THE FDSS µCELL/EFS: A NEW HIGH-THROUGHPUT SCREENING PLATFORM FOR EARLY MUSCLE DRUF DISCOVERY

Jean-Marc d'Angelo¹, Melanie Flaender², Pauline Poydenot²

¹HAMAMATSU Photonics France S.A.R.L., Massy, France, ²CYTOO SA, Grenoble Cedex, France

ELECTRICAL STIMULATION OF THE MYOSCREEN™ PLATFORM WITH THE FDSS pCELL/EFS: A NEW HIGH-THROUGHPUT SCREENING PLATFORM FOR EARLY MUSCLE DRUG DISCOVERY

ELECTRICAL STIMULATION OF THE MYOSCREEN™ PLATFORM WITH THE FDSS pCELL/EFS: A NEW HIGH-THROUGHPUT SCREENING PLATFORM FOR EARLY MUSCLE DRUG DISCOVERY [2.4 MB/PDF]

Ca2+ Oscillation Responses of a hIPSC Derived Neuro-spheriod Model and Primary Mouse Cortical Neuron Model for Derisking Drug-Induced Seizure Liability: a Comparative Study in the Framework of the IMI2-NeuroDeRisk Project

John Imredy¹, Gautier Roussignol², Holly Clouse¹, Ludmilla Mazelin- Winum²

¹Merck & Co., Inc., Rahway, New Jersey, USA, ²Sanofi R&D, Montpellier, France

Ca2+ Oscillation Responses of a hIPSC Derived Neuro-spheriod Model and Primary Mouse Cortical Neuron Model for Derisking Drug-Induced Seizure Liability: a Comparative Study in the Framework of the IMI2-NeuroDeRisk Project

Ca2+ Oscillation Responses of a hIPSC Derived Neuro-spheriod Model and Primary Mouse Cortical Neuron Model for Derisking Drug-Induced Seizure Liability: a Comparative Study in the Framework of the IMI2-NeuroDeRisk Project [88.1 MB/PDF]

Testimonials

WCAG-AA Testimonial Slider

Thierry Calmels portrait

"The conferences given are chosen to present different fields of expertise and enable us to maintain our technological watch on current hot topics. These meetings encourage exchanges and knowledge-sharing between users, all in a relaxed atmosphere. It's a great opportunity to build up a network of contacts with top-quality researchers from a wide range of backgrounds, including academia, bio-tech and pharmaceutical companies."

Thierry Calmels

Bioprojet Biotech

Paris, France

Dr. Geert Bultynck portrait

"It was a true pleasure to welcome the FDSS users meeting in the beautiful Old Beguinage, Leuven, Belgium. The highly attended event provided an exhilarating glimpse into the future of FDSS systems. The atmosphere at the meeting was marked by convivial and collegial interactions with openly shared experiences and insightful discussions."

Dr. Geert Bultynck

KU Leuven

Leuven, Belgium

Vincent Jaquet portrait

"This meeting is one of my preferred meetings because of the quality and diversity of the science and the participants. The science is great and the atmosphere is friendly, which favours exchanges of ideas and technical tips."

Vincent Jaquet

Department of Pathology & Immunology, Centre médical universitaire

Genève, Switzerland

Gautier Roussignol portrait

"The FDSS Users Meeting is a very interesting meeting, with a lot of concrete applications and insights on either new application or how others areA are performing their own use which may also rise new ideas. The meeting also allows room for direct interaction."

Gautier Roussignol

Sanofi R&D

Montpellier, France

Past/Other Events

2022 FDSS Users Meeting in Geneva, Switzerland

2025 Drug Discovery Workshop in Tübingen, Germany

If you have questions regarding the upcoming event or past events, please contact us.