ORCA-Fusion Digital CMOS camera


The ORCA-Fusion, built from the sensor up, balances the complex nuances of camera features to provide beautiful images and robust data at all lights levels, but especially in tough low-light conditions. The exceptionally low and highly uniform read noise of the ORCA-Fusion means that when the sample emits even just a handful of photons, either by default or by experimental design, they are not lost in the noise, but detected and reliably quantified. After all, when you want to hear a whisper it’s best to be in a quiet place.

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This site provides information on scientific cameras.
Since there is a wide range of camera types and performance, it is important to select the best camera for each application.
It introduces technical information, simulation tools, and examples of actual applications to help you fully understand the performance of the camera and select the best one for your application.

Special site for Scientific cameras


  • High resolution : 2304 × 2304 (5.3 Megapixels)
  • High speed : 100 frames/s (at 2304 × 2048 ROI)
  • Dynamic range : 21,400:1
  • Pixel size : 6.5 μm × 6.5 μm
  • Read noise : 0.7 electrons, rms (Ultra quiet Scan)
  • Prnu : 0.06 % (@ 7500 electrons)
  • DSNU : 0.06 electrons
  • Peak QE : 80 %
  • Patented Tools for Advanced Imaging: Lightsheet Readout Mode

Lightsheet Readout Mode [Patented]

“Lightsheet Readout Mode” is a unique and patented feature of Hamamatsu sCMOS cameras which can improve signal to noise ratios in Lightsheet microscopy.
For more information about the principle and features of Lightsheet Readout Mode, please see details from below.

What is Lightsheet Readout Mode?

Lightsheet Readout Mode

PC recommendations

With the introduction of the ORCA-Fusion, users are now able to stream 5 megapixel images to their computers 89 frames per second. The computer recommendations for this high data rate can be met by using the guidelines listed this PC Recommendations for ORCA-Fusion.


Our software provides the interface to access all of our carefully engineered camera features, from simply setting exposure to orchestrating complex triggering for multidimensional experiments.

We have designed a Software API to be used by all Hamamatsu digital cameras, named DCAM-API, and designed a Software Development Kit for the integration of Hamamatsu cameras with custom software.

Third party software

As imaging setups become more complex, software has to control not only a camera, but also many other devices such as microscopes, stages and filter wheels… Therefore, companies have integrated Hamamatsu DCAM based cameras into their software products.


Type number C14440-20UP
Imaging device sCMOS
Effective no. of pixels 2304(H)×2304(V)
Cell size 6.5 μm(H)×6.5 μm(V)
Effective area 14.976 mm (H)×14.976 mm (V)
Full well capacity 15 000 electrons *1
Readout speed Fast scan: 11.22 ms (89.1 frames/s with CoaXPress or 31.6 frames/s with USB 3.0) (2304 x 2304) *5
Standard scan: 42.99 ms (23.2 frames/s with CoaXPress or USB 3.0) (2304 x 2304) *5
Ultra quiet scan: 184.4 ms (5.4 frames/s with CoaXPress or USB 3.0) (2304 x 2304) *5
Readout noise Fast scan:1.4 electrons rms *1
Standard scan:1.0 electrons rms *1
Ultra quiet scan:0.7 electrons rms *1
Exposure time Fast scan: 17 μs to 10 s (4.87 μs step)
Standard scan: 65 μs to 10 s (18.65 μs step)
Ultra quiet scan: 280 μs| 10 s (80.00 μs step)
Cooling method Peltier cooling
Cooling temperature Forced-air cooled: -5 ˚C (Ambient temperature: +25 ˚C)
Water cooled: -5 ˚C (Water temperature: +25 ˚C)
Water cooled (Max cooling): Less than -15 ˚C *1,*3
Dark current Cooling temperature(-5 ˚C): 0.5 electrons/pixel/s *1,*4
Cooling temperature(-15 ˚C): 0.2 electrons/pixel/s *1,*4
Dynamic range 21 400 : 1 *1,*2
External trigger mode Edge, Level, Sync readout, Start, Global reset edge, Global reset level
External trigger signal routing SMA
Trigger delay function 0 s to 10 s in 1 μs steps
Trigger output 3 programmable timing, Global exposure timing, trigger ready, low, high
External signal output routing SMA
Interface CoaXPress (Dual CXP-6) and USB 3.0 *6
A/D converter 16 bit / 12 bit / 8 bit
Lens mount C-mount
Power supply Approx. 150 VA *7
Ambient operating temperature 0 ˚C to + 40 ˚C
Ambient operating humidity 30 % to 80 %, with no condensation

*1 Typical value
*2 Calculated from the ratio of the full well capacity and the readout noise
*3 The water temperature is +20 ˚C and the ambient temperature is +20 ˚C
*4 Dark current depends on cooling temperature
*5 Valid to 4 digits and rounded up to 5th digit
*6 USB 3.1 Gen 1 compatible
*7 The value with AC 240 V. (Approx. 70 VA with AC 100 V)

Spectral response


Instruction manual

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