ORCA-Fusion Digital CMOS camera


The ORCA-Fusion, built from the sensor up, balances the complex nuances of camera features to provide beautiful images and robust data at all lights levels, but especially in tough low-light conditions. The exceptionally low and highly uniform read noise of the ORCA-Fusion means that when the sample emits even just a handful of photons, either by default or by experimental design, they are not lost in the noise, but detected and reliably quantified. After all, when you want to hear a whisper it’s best to be in a quiet place.

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  • High resolution : 2304 x 2304 (5.3 Megapixels)
  • High speed : 100 frames/s (at 2304 X 2048 ROI)
  • Dynamic range : 21,400:1
  • Pixel size : 6.5 μm X 6.5 μm
  • Read noise : 0.7 electrons, rms (Ultra-quiet Scan)
  • Prnu : 0.06 % rms (@ 7500 electrons)
  • DSNU : 0.3 electrons rms
  • Peak QE : 80 %
  • Patented Tools for Advanced Imaging: Lightsheet Readout Mode

Lightsheet Readout Mode [Patented]

“Lightsheet Readout Mode” is a unique and patented feature of Hamamatsu sCMOS cameras which can improve signal to noise ratios in Lightsheet microscopy.
For more information about the principle and features of Lightsheet Readout Mode, please see details from below.

What is Lightsheet Readout Mode?

Lightsheet Readout Mode

PC recommendations

With the introduction of the ORCA-Fusion, users are now able to stream 5 megapixel images to their computers 89 frames per second. The computer recommendations for this high data rate can be met by using the guidelines listed this PC Recommendations for ORCA-Fusion.


Type number C14440-20UP
Imaging device sCMOS
Effective no. of pixels 2304(H)×2304(V)
Cell size 6.5 μm(H)×6.5 μm(V)
Effective area 14.976 mm (H)×14.976 mm (V)
Full well capacity 15 000 electrons *1
Readout speed Fast scan: 11.22 ms (89.1 frames/s with CoaXPress or 31.6 frames/s with USB 3.0) (2304 x 2304) *5
Standard scan: 42.99 ms (23.2 frames/s with CoaXPress or USB 3.0) (2304 x 2304) *5
Ultra-quiet scan: 184.4 ms (5.4 frames/s with CoaXPress or USB 3.0) (2304 x 2304) *5
Readout noise Fast scan:1.4 electrons rms *1
Standard scan:1.0 electrons rms *1
Ultra-quiet scan:0.7 electrons rms *1
Exposure time Fast scan: 17 μs to 10 s (4.87 μs step)
Standard scan: 65 μs to 10 s (18.65 μs step)
Ultra-quiet scan: 280 μs| 10 s (80.00 μs step)
Cooling method Peltier cooling
Cooling temperature Forced-air cooled: -5 ˚C (Ambient temperature: +25 ˚C)
Water cooled: -5 ˚C (Water temperature: +25 ˚C)
Water cooled (Max cooling): Less than -15 ˚C *1,*3
Dark current Cooling temperature(-5 ˚C): 0.5 electrons/pixel/s *1,*4
Cooling temperature(-15 ˚C): 0.2 electrons/pixel/s *1,*4
Dynamic range 21 400 : 1 *1,*2
External trigger mode Edge, Level, Sync readout, Start, Global reset edge, Global reset level
External trigger signal routing SMA
Trigger delay function 0 s to 10 s in 1 μs steps
Trigger output Global exposure timing, trigger ready, low, high
External signal output routing SMA
Interface CoaXPress (Dual CXP-6) and USB 3.0 *6
A/D converter 16 bit / 12 bit / 8 bit
Lens mount C-mount *7
Power supply Approx. 150 VA *8
Ambient operating temperature 0 ˚C to + 40 ˚C
Ambient operating humidity 30 % to 80 %, with no condensation

*1 Typical value
*2 Calculated from the ratio of the full well capacity and the readout noise
*3 The water temperature is +20 ˚C and the ambient temperature is +20 ˚C
*4 Dark current depends on cooling temperature
*5 Valid to 4 digits and rounded up to 5th digit
*6 USB 3.1 Gen 1 compatible
*7 F-mount (C14440-20UP01)
*8 The value with AC 240 V. (Approx. 70 VA with AC 100 V)

Spectral response


Instruction manual

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