MAICOは励起・蛍光波長1種ごとに必要な構成部品をひとまとめにしたサブユニット構造を採用しています。
サブユニット構造を採用したことで、例えば、初期投資を抑えるために初回購入時は波長の数を絞り、研究の進展にあわせて波長を追加、といった購入方法の選択も可能です。
最大4つのサブユニットを搭載することができ、単波長の観察から、4波長(405 nm、488 nm、561 nm、638 nm)の多波長同時観察まで対応します。
小型MEMSミラーを走査素子に採用し、専用の内蔵レーザ光源を開発しました。その結果、329 mm(W)× 150 mm(H)×300 mm(D)のコンパクトサイズを実現しました。
波長の追加も筐体内のサブユニットを増やすことで完結するため、新たな装置を取り付けたりすることなく、実験台の限られたスペースに配置することができます。
MAICOはピンホールを使用して光学的切片像を取得する、ゴールドスタンダードの共焦点光学系です。
厚みのある蛍光試料を撮像するとき、対物レンズの焦点面から発せられた蛍光だけがピンホールを通過して検出器に届き、焦点面から深さ方向に離れた位置から発せられた蛍光は遮断されます。
定量性・再現性・信頼性の高い信号を検出し、デコンボリューションなどの画像処理を行うことなく、コントラストの高い画像を取得することができます。
29 kHzのレゾナントタイプの弊社製高速MEMS※ミラーを採用。最大で76フレーム/秒のハイスピードスキャンを実現し、Ca2+イメージング等の高速現象に対応します。
高速なレゾナントスキャナを用いることでレーザ光照射時間を短縮できるので、ライブセルはもちろん固定標本を観察する場合でも、光毒性や退色を抑えた効率の良い計測を行うことができます。
また、ハイスピードスキャンにより、試料の移動やフォーカス合わせの際に、高解像度かつ表示の遅延が少ない快適な観察が可能です。
浜松ホトニクスの世界最高レベルの感度を持つ検出器と信号処理のノウハウを生かし、レーザ光の出力をクラス3Rまで低出力化することに成功しました。一般的な共焦点顕微鏡のようなレーザ管理区域を必要とせず、普段と変わらない環境で使用することができます。
MAICOは弊社共通カメラライブラリである「DCAM-API」によってサポートされており、弊社製ソフトウエアHCImageで制御できます。また、DCAM-APIに対応しているサードパーティソフトウエアや自作ソフトウエアで画像取得が可能です。
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